The Century of Biology

Going Founder Mode On Cancer

Sid Sijbrandij's extraordinary care journey

Jan 18 • Elliot Hershberg

264

31

60

November 2025

On AI Infrastructure in Biology

Three stories; six parameters

Nov 23, 2025 • Elliot Hershberg

228

20

23

September 2025

Manifold Bio: Barcoded Biologics

Designing medicines that go where we want them to

Sep 28, 2025 • Elliot Hershberg

77

14

8

June 2025

What Are Virtual Cells?

Learning "universal representations" of life's fundamental unit

Jun 29, 2025 • Elliot Hershberg

110

11

13

March 2025

On Modality Commoditization

And what might come next

Mar 16, 2025 • Elliot Hershberg

121

5

9

February 2025

Hub-and-Spoke Biotechs: BridgeBio

Attempting "Moneyball for biotech"

Feb 16, 2025 • Elliot Hershberg

93

18

9

October 2024

Hub-and-Spoke Biotechs: Nimbus Therapeutics

Building an "evergreen" drug discovery engine

Oct 20, 2024 • Elliot Hershberg

69

16

7

September 2024

Living Carbon: Photosynthesis-Enhanced Trees

Why and how to engineer trees; climate biotech business strategy

Sep 22, 2024 • Elliot Hershberg

65

17

3

June 2024

A Summer Hiatus

Pausing before scaling

Jun 23, 2024 • Elliot Hershberg

57

9

Scaling CRISPR Cures

Realizing the potential of genetic medicine

Jun 2, 2024 • Elliot Hershberg

62

16

7

May 2024

Generating (Somewhat) New Biology with AI

Using protein language models for Digital Evolution

May 5, 2024 • Elliot Hershberg

55

16

2

April 2024

Compounding Until Inflection

Present vs. future platform value

Apr 14, 2024 • Elliot Hershberg

35

2

1