Loved it. Recently read "What to make of a life" by Jim Collins and he covers Barbara's work brilliantly so great to see Cold Spring Harbor as so relevant today.
The shift from static predictions to dynamic modeling and agentic science is genuinely transformational at the discovery layer, and the CSHL thesis is convincing. The question I keep returning to is what happens when these computationally designed molecules hit the manufacturing handoff, where 50% of bioprocessing sites still run on paper and the data infrastructure to translate an AI-discovered candidate into a scaled therapeutic product does not yet exist at most CDMOs.
Loved it. Recently read "What to make of a life" by Jim Collins and he covers Barbara's work brilliantly so great to see Cold Spring Harbor as so relevant today.
The shift from static predictions to dynamic modeling and agentic science is genuinely transformational at the discovery layer, and the CSHL thesis is convincing. The question I keep returning to is what happens when these computationally designed molecules hit the manufacturing handoff, where 50% of bioprocessing sites still run on paper and the data infrastructure to translate an AI-discovered candidate into a scaled therapeutic product does not yet exist at most CDMOs.
The development of AI agents in biomedicine has been fascinating! Thanks for the nice summary!
What an exciting time in biology research! What an amazing place Cold Springs Harbor Laboratories is past, present and future!
Beautiful summary. Thanks Elliot!
Thanks for the great summary.